Dissolution
In order to properly test the dissolution of an active ingredient in a specified medium, with a given apparatus over a specific time period, R.D. Laboratories utilizes HPLC UV-VIS Spectrophotometry. This may be a one-point measurement or multi-point timed-release determination.
We perform dissolution on a wide range of finished dosage forms, although clients often request analyzation of tablets and capsules. Most commonly, we use Apparatus 1 (Basket) and Apparatus 2 (Paddle). Dissolution testing is critical in determining that active drugs have been released from the dosage form.